Table 1.
Pre‐ and post‐bronchodilator spirometry and body plethysmography.
| Parameter | Prior to endobronchial valve insertion | 4 weeks after endobronchial valve insertion |
|---|---|---|
| FEV1 | 0.7 L (26% predicted) | 0.7 L (25% predicted) |
| FVC | 2.4 L (63% predicted) | 2.3 L (62% predicted) |
| FEV1/FVC | 31% | 32% |
| DLCO (unadjusted for haemoglobin) | 16 mL/mmHg/min (64% predicted) | 11 mL/mmHg/min (44% predicted)* |
| KCO | 3.9 mL/mHg/min/L (103% predicted) | 3.1 mL/min/mHg/min (84% predicted) |
| VA | 4.2 L (62% predicted) | 3.5 L (52% predicted) |
| TLC | 7.8 L (116% predicted) | 7.4 L (110% predicted) |
| RV | 4.9 L (187% predicted) | 5.0 L (190% predicted) |
| RV/TLC | 62% predicted | 67% predicted |
| 6‐min walk distance | 160 m | 280 m |
| Resting spo2, spo2 nadir | 92%, 90% at 1 min | 94%, 91% at 4 min |
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.
*
DLCO likely underestimated as patient did not inhale to >85% FVC; at 5 months, repeat DLCO was 58% predicted.