Table 1.
Criteria | Stringent API5 | Loose API5 | Modified API6, 7 |
---|---|---|---|
Wheezing | Early (≤3 years) frequent wheezing* | Early (≤3 years) wheezing | ≥4 episodes/yr during first 3 years of life |
Major criteria | |||
Parent with asthma | Yes | Yes | Yes |
MD-diagnosed Atopic dermatitis | Yes | Yes | Yes |
Sensitization to ≥1 aeroallergen | Not included | Not included | Yes |
Minor criteria | |||
Wheezing unrelated to colds | Yes | Yes | Yes |
Blood eosinophils ≥4% | Yes | Yes | Yes |
MD-diagnosed Allergic rhinitis | Yes | Yes | Not included |
Sensitization to foods (milk, egg, peanut) | Not included | Not included | Yes |
For a positive API in each version, children must meet the wheezing criterion as well as at least 1 major criterion or at least 2 minor criteria. |
Score of ≥3 on scale of 1–5 for wheezing (1 = ”very rarely”, 5 = ”most days”).