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Effect of Mcc950 on high-glucose-stimulated NLRP3 inflammasome mRNA expression in HRECs. (a–c) Relative mRNA expression level of NLRP3, caspase1 and IL-1β was quantified. Expression is shown relatively to β-actin in each group, which was set to 1. Data are shown as mean±S.E.M., n=3 technical replicates. Significant differences were calculated using one-way ANOVA followed by Tukey’s multiple comparison test. *P<0.01 versus control
