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. 2017 Jul 20;8(7):e2948. doi: 10.1038/cddis.2017.344

Figure 2.

Figure 2

T cells from thymus and spleen are able to transform the inactive metabolite 11-DHC into active corticosterone. Supernatants from overnight cultures of thymocytes (a) or sorted splenic CD4+ and CD8+ (b) cells either untreated (open bars) or treated with 11-DHC in the absence (black bars) or presence (gray bars) of GA were analyzed for corticosterone content by ELISA. Mean values±S.E.M. from at least three independent experiments are shown