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. 2017 Jun 12;6(7):1084–1095. doi: 10.1242/bio.026120

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — GATA6 is bound to definitive endoderm-enriched genes. (A) Workflow used to identify GATA6 occupied sequences throughout the genome at day 4 of differentiation. (B) Two examples showing the position of GATA6-enriched sequences (peaks) within the DKK1 and DKK4 genes. (C) Synopsis of the number of GATA6 peaks identified by ChIP-seq and the corresponding number of unique genes. (D) Pie chart showing the percentages of GATA6 binding across annotated genomic regions. (E) Distribution of GATA6 peaks relative to the transcriptional start site of the nearest gene. (F) Consensus GATA6 binding site across all peaks. (G) Venn diagram showing the overlap between genes bound by GATA6 and definitive endoderm-enriched genes.