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. 2017 Jun 12;6(7):1084–1095. doi: 10.1242/bio.026120

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© 2017. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 5. — GATA6 directly binds genes encoding members of the endoderm transcription factor network. (A) Heatmap showing relative mRNA levels encoding definitive endoderm-enriched transcription factors within GATA6 (+) and GATA6 (−) cells at day 4 of endoderm differentiation. The huESC-derived definitive endoderm-enriched genes shown were identified as transcription factors by the Broad Institute's MSig Database (see Table S4B,H). (B) Integrated genome viewer captures showing representative definitive endoderm-enriched transcription factors that exhibit GATA6 occupancy.