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. 2017 Jul 5;14(132):20170126. doi: 10.1098/rsif.2017.0126
Algorithm MCAP
input:
Monte Carlo profile Inline graphic evaluated at ϕ1:K
Local quadratic regression smoother, S
Smoothing parameter, λ
Confidence level, 1 − α
output:
Cut-off, δ, for a Monte Carlo profile likelihood confidence interval
algorithm:
Fit a local quadratic smoother, Inline graphic
Obtain Inline graphic
Obtain regression weights w1:K for the evaluation of Inline graphic at Inline graphic
Fit a linear regression model, Inline graphic, with weights w1:K
Obtain regression estimates Inline graphic and Inline graphic
Obtain regression covariances Inline graphic, Inline graphic, Inline graphic
Let Inline graphic
Let χα be the (1 − α) quantile of the χ-square distribution on one degree of freedom
Let Inline graphic