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. 2017 Aug 9;8:44. doi: 10.1186/s13229-017-0161-9

Table 3.

Family-based association results of polymorphisms in AVPR1A with single quantitative trait by additive model

Traits SCQ ASDS SRS K-CBCL ADIR-A1 ADIR-A2 ADIR-A3 ADIR-A4 ADIR-total VABS
Marker Freq. N p p p p p p p p p p
rs7294536 G 0.193 71 0.049 0.019 0.033 0.015 0.016 0.029 0.030 0.019 0.021 0.407
rs7294536 A 0.807 71 0.049 0.019 0.033 0.015 0.016 0.029 0.030 0.019 0.021 0.407
rs10877969 G 0.089 47 0.001 < 0.001 < 0.001 < 0.001 0.001 0.001 0.001 0.002 0.001 < 0.001
rs10877969 A 0.911 47 0.001 < 0.001 < 0.001 < 0.001 0.001 0.001 0.001 0.002 0.001 < 0.001

Freq. allele frequency, N number of informative nuclear families, p p value, SCQ Social Communication Questionnaires, ASDS Asperger Syndrome Diagnostic Scale, SRS social responsiveness scale, K-CBCL Korean Child behavior checklist (social problems), K-ADIR Autism Diagnostic Interview-Revised, ADI-A1 failure to use nonverbal behaviors to regulate social interaction, ADI-A2 failure to develop peer relationship, ADI-A3 lack of shared enjoyment, ADI-A4 lack of socioemotional reciprocity, VABS Vineland Adaptive Behavior Scales