Table 1.
Cognitive domain and subdomaina | Cognitive tests | First author, publication date [reference] |
---|---|---|
Dementia screening | MMSE | Folstein, 1975 [22] |
Memory | ||
Verbal spana | VLMT trial 1 | Helmstaedter, 2001 [46] |
CERAD wordlist trial 1 | Aebi, 2002 [47] | |
Verbal learninga | VLMT trial 1–5 | see above |
CERAD wordlist trial 1–3 | see above | |
Verbal recalla | VLMT trial 6 | see above |
CERAD wordlist recall | see above | |
Verbal recognitiona | VLMT trial 8 true | see above |
CERAD wordlist recognition % | see above | |
Visual recalla | CFT 3-minute recall | Meyers, 1996 [48] |
CERAD figure recall | see above | |
Language | ||
Object naminga | Wortproduktionsprüfung (Word Production Test) | Blanken, 1999 [49] |
CERAD Boston naming test 15 | see above | |
Visuospatial skills | ||
Figure copya | CFT copy | see above |
CERAD figure copy | see above | |
Executive function | ||
Semantic word fluency a | RWT- 1 minute category fluency “animals” | Aschenbrenner, 2000 [50] |
Phonematic word fluency a | RWT- 1 minute letter fluency “S” | see above |
Set shiftinga | TMT B | Tombaugh, 2004 [51] |
Digit span backwardsa | Wechsler Memory Scale – backward digit span | Härting, 2000 [52] |
Attention | ||
Processing speeda | TMT A | see above |
Praxis | ||
Pantomime of object usea | Cologne Apraxia Screening 1.1 and 1.2. | Weiss, 2013 [53] |
Imitation of limb posturesa | Cologne Apraxia Screening 2.2 | see above |
Imitation of face posturesa | Cologne Apraxia Screening 2.1 | see above |
Social cognition | ||
Facial emotion recognitiona | Ekman Facial Emotion Recognition test (SEA) | Funkiewiez, 2012 [54] |
Abbreviations: CERAD Consortium to Establish a Registry for Alzheimer’s Disease neuropsychological test battery, CFT Complex Figure Test, MMSE Mini Mental State Examination, RWT Regensburg Word Fluency Test, SEA Social Cognition and Emotional Assessment, TMT Trail Making Test, VLMT Verbal Learning and Memory Test
Column 1 displays all covered cognitive domains (bold) and subdomains. Column 2 displays the incorporated tests to cover the respective subdomains. Italicised tests display the alternative test set, which was employed for patients >65 years of age (Alzheimer’s disease 18 of 43, behavioural variant of frontotemporal dementia 4 of 26). For inter-test and inter-subdomain comparability in statistical analysis, individual test raw scores were z-transformed. Column 3 presents the first author’s name and the publication date of the normative data we used to estimate patients’ test performance
aUsed for statistical analysis