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WF-A trigger the apoptosis through caspase-3, cyt-c, and PARP activation. (A) WF-A activates the caspase-3 in a dose-dependent manner leading to apoptosis at IC50. (B) In western blot analysis, WF-A-treated cells showed the activation of caspase-3, cytosolic cyt-c, and PARP in a time-dependent manner
