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. Author manuscript; available in PMC: 2018 Aug 3.
Published in final edited form as: Nanoscale. 2017 Aug 3;9(30):10906–10918. doi: 10.1039/c7nr03306k

Figure 5.

Figure 5

Uptake of Dox from polymer-Dox conjugates (upper row) and co-localization of Dox and polymer carrier labeled with Dyomics-633 (lower row). Fluorescent dye Dyomics-633 colored in red, Dox colored in green, nucleus stained with Hoechst 33342 colored in blue, colocalization of Dox and polymer colored in yellow, colocalization of Dox Hoechst 33342 in nucleus is colored in light blue. Pictures determined after incubation of parental murine mammary 4T1 cell line for 24 hours with fluorescently labeled polymer-drug conjugates A) HD-P+Dox/Dy-633, B),D) LD-P-30+Dox/Dy-633 and C), E) LD-P-45+Dox/Dy-633 at 37°C and 5 % CO2.