. Author manuscript; available in PMC: 2018 Aug 3.

Published in final edited form as: Nanoscale. 2017 Aug 3;9(30):10906–10918. doi: 10.1039/c7nr03306k

Table 1.

Characteristics of the linear HPMA copolymer precursors and the polymer-drug conjugates

Copolymer No.	Polymerization type	M_w^a (kg/mol)	Đ^a	Content of functional groups^b (mol%)

				Hydrazides	TT
HD-P(hyd)	FRP	27.8	1. 74	5.1	-
HD-P(TT)	FRP	25.6	1.54	-	1.7
LD-P(hyd)-30	RAFT	32.6	1.12	7.7	-
LD-P(TT)-30	RAFT	33.3	1.06	-	1.7
LD-P(hyd)-45	RAFT	45.2	1.13	6.9
LD-P(TT)-45	RAFT	43.3	1.07	-	3.6

The molecular weights (M_w) and dispersity (Đ) were determined by SEC using RI and MALS detection.

The content of hydrazide or TT groups was determined spectrophotometrically.