Skip to main content
. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2017 Jun 3;108:158–169. doi: 10.1016/j.yjmcc.2017.05.013

Figure 9. NKA isoform distribution in mouse ventricular myocytes.

Figure 9

A: This cartoon illustrates the structural conclusions that NKA-α1 (blue circles) is relatively uniform along the entire sarcolemma (surface as well transverse and axial TT components), whereas NKA-α2 (red circles) is especially concentrated in the transverse TT components. B: Blocking all of the NKA-α2 (black circles) would suppress total NKA transport by ∼50% in TT, with limited impact on transport in surface or longitudinal (axial) TT regions. C: Conversely, blocking 33% of NKA-α1 would suppress total NKA transport by nearly 33% at the surface and axial TT regions, but only by ∼17% in the transverse TT region.