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Progression of retinal failure in diabetes. Retinal failure occurs after long-term decompensated adaptive responses to metabolic dysfunction. The top image shows compensated diabetic retinopathy in a patient with mild non-proliferative diabetic retinopathy. The bottom images are examples of decompensated non-proliferative retinopathy with macular edema (lower left) and proliferative diabetic retinopathy with preretinal hemorrhage (lower right). From Gray (22) with permission.
