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. Author manuscript; available in PMC: 2017 Aug 10.
Published in final edited form as: Nat Rev Rheumatol. 2015 Mar 24;11(5):301–312. doi: 10.1038/nrrheum.2015.29

Figure 6.

Figure 6

Autoantibody sequential studies and clinical evaluation of women who have babies with CHB of any degree, EFE or congenital valvular disease in an otherwise structurally-normal fetal heart. For women with negative results in Ro/La commercial tests, we recommend extending immunological studies to include anti-Ro52 and anti-Ro60 antibodies using a native antigen. *Systemic autoimmune diseases more frequently identified in CHB-affected mothers. Abbreviations: CHB, congenital heart block; EFE, endocardial fibroelastosis, pSS, primary Sjögren syndrome; SLE, systemic lupus erythematosus.