Table 3.
Organ lesion scores in control and different experimental groups.
Lesion | Experimental groups | |||
---|---|---|---|---|
Control | MTX | MTX-DM50 | MTX-DM100 | |
Hepatic lesions | 0.00 | 3.00 ± 0.00∗ | 1.80 ± 0.13∗# | 1.20 ± 0.13∗# |
Renal lesions | 0.00 | 3.00 ± 0.00∗ | 2.30 ± 0.15∗# | 1.90 ± 0.31∗# |
Cardiac lesions | 0.00 | 3.00 ± 0.00∗ | 2.00 ± 0.21∗# | 1.40 ± 0.16∗# |
Data are expressed as means ± SEM. ∗Significant change at p < 0.01 with respect to the negative control group. #Significant change at p < 0.01 with respect to the MTX group as the positive control group.