Condition and Definition
Diabetes (≥ 1 of the following):
• Hemoglobin A1C ≥ 6.5
• Fasting glucose ≥ 126
• Random glucose ≥ 200 on 2 or more occasions
• Prescription for insulin outside of pregnancy
• ICD-9 code 250.xx or ICD-10 code E10*, E11*, or E14* on 2 or more occasions
• Prescription for glyburide, gliclazide, glipizide, glimepiride, pioglitazone, rosiglitazone, repaglinide, nateglinide, meglitinide, sitagliptin, exenatide, alogliptin, linagliptin, saxagliptin, albiglutide, dulaglutide, liraglutide, canagliflozin, dapagliflozin, empagliflozin, or pramlintide
Asthma (≥ 1 of the following):
• ≥ 2 encounters with diagnosis code for asthma (ICD-9 493.xx or ICD-10 J45*–J46*)
• ≥ 2 prescriptions for albuterol, levalbuterol, pirbuterol, arformoterol, formoterol, indacaterol, salmeterol, beclomethasone, inhaled budesonide, inhaled ciclesonide, inhaled flunisolide, inhaled fluticasone, inhaled mometasone, montelukast, zafirlukast, zileuton, ipratropium, tiotropium, cromolyn INH, omalizumab, fluticasone + salmeterol, albuterol + ipratropium, mometasone + formoterol, or budesonide + formoterol
Smoking:
• Most recent smoking status of “current” as recorded in the EHR “tobacco” field (synonyms for current acceptable)
Hypertension (≥ 1 of the following):
• Systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 on ≥ 2 occasions within a 1-y period
• Diagnosis code for hypertension (ICD-9 401.xx or 405.xx or ICD-10 I10 or I15) and prescription for at least 1 of the following medications within 1 y of the hypertension diagnosis code: hydrochlorothiazide, indapamide, amlodipine, clevidipine, felodipine, isradipine, nicardipine, nifedipine, nisoldipine, diltiazem, verapamil, acebutolol, atenolol, betaxolol, bisoprolol, carvedilol, labetolol, metoprolol, nadolol, nebivolol, pindolol, propranolol, benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan, clonidine, doxazosin, guanfacine, or methyldopa
Obesity:
• Most recent BMI ≥ 30 kg/m2
• If BMI not available, calculate using last available weight measured within the last y and last available height measured when aged ≥ 16 y

Note. ICD-9 (10) = International Classification of Diseases, Ninth (Tenth) Revision; EHR = electronic health record; BMI = body mass index (defined as weight in kilograms divided by the square of height in meters).