Table 5. Binding Constants for Binding of TGF-β2 and TGF-β2TM to TβRII in the Presence and Absence of BGO.
surface | analyte | KD (nM) | Rmax (RU) |
---|---|---|---|
TGF-β2 | TβRII | 4600 ± 700 | 142 ± 13 |
TGF-β2 | TβRII (800 nM BGO) | 130 ± 100 | 320 ± 13 |
TGF-β2TM | TβRII | 145 ± 17 | 720 ± 20 |
TGF-β2TM | TβRII (800 nM BGO) | 30 ± 5 | 1000 ± 30 |