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Effect of Foscarnet on polymerase and exonuclease activities under processive conditions. UL30 was incubated with DNA15C (1 μM) in the presence of 0 μM or 10 μM dNTPs, and 0–80 μM Foscarnet Aliquots were analyzed at 6 min. (A) Phosphorimages of the products of DNA15C full extension and degradation using UL30. (B) Plot of exonuclease products as a function of PFA concentration.
