Figure 5.
Tumor response after receiving different treatments. The tumor model was established by s.c. injection of UMSCC 22A cells in the flanks of mice. (A) Thermal image of mice after receiving NIR irradiation over 10 min (2.83 W/cm2). (B) The tumor volume change profiles of mice after receiving different treatments. Insert shows the representative images of tumors harvested from different treatment groups at the end of the experiment. Data were expressed as mean ± SD (DOX@PLGA/PD-C NIR vs DOX, *P < 0.05). (C) The body weight curves of tumor-bearing mice after receiving different treatments. (D) Representative images of developed tumors after receiving DOX treatment. (E) Representative images of developed tumors after receiving DOX@PLGA/PD-C NIR treatment. Circles in (D) and (E) indicate the location of the tumor.