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. 2017 Aug 7;216(8):2551–2564. doi: 10.1083/jcb.201612042

Table 2. Curve fitting of FRAP data.

GFP-actin F(0) F(e) c τ1 (sec) τ2 (sec)
Control WT 0.0960 0.8797 0.4161 1.5112 44.0287
G13R 0.1041 1.0019 0.4637 1.4744 69.3191
R62D 0.1021 1.0002 0.4506 1.5724 70.2468
DMSO G13R 0.10126 1.0006 0.45883 1.5190 69.4147
R62D 0.098472 1.0035 0.45535 1.5174 72.7302
LY294002 G13R 0.1274 1.0004 0.34306↓ 1.3793 69.8583
R62D 0.16293 0.99987 0.3464↓ 1.4974 68.949
SF1670 G13R 0.087312 0.9997 0.57153↑ 1.6203 70.3258
R62D 0.081741 1.0016 0.57138↑ 1.5003 70.0223
Scramble RNAi G13R 0.099384 0.99966 0.45277 1.5389 70.3558
R62D 0.098478 1.0030 0.45301 1.5687 72.6469
Profilin 1/2 RNAi G13R 0.16664 0.9999 0.17228↓ 1.5483 72.8719
R62D 0.16208 1.0016 0.17482↓ 1.5657 74.7082

The comprehensive table summarizes all five parameters (F[0], F[e], c, τ1, and τ2) of the double exponential function used to fit the FRAP curves of WT actin or actin mutants. Note that τ1 and τ2 are similar among actin mutants under different conditions. Arrows indicate the changes with bold numbers depicting an increase over the control.