Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 7;216(8):2295–2304. doi: 10.1083/jcb.201612165

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Hamdan et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Figure 3. — Selected chaperones reduce protein aggregation in a hac1 mutant. (A) Turnover rate of ΔssCPY^∗-GFP in wild-type, hac1, and hrd1 strains (n = 3) ± SD. (B) Turnover rate of Hmg2-myc in wild-type and hac1 strains (n = 3) ± SD. (C) The overlap between chaperones identified within the protein aggregate datasets of the wild-type, hac1, and hrd1 strains. The 21 chaperones listed were present in the aggregates of all strains. (D) Silver staining of protein aggregates isolated from the hac1 mutant containing galactose-regulatable expression plasmids for Ssa1, Ydj1, Sis1, Hsp104, Sse1, or Ssb1. Vector denotes an empty vector control. (E) Turnover rate of ΔssCPY^∗-GFP in wild-type and hac1 strains containing galactose-regulatable expression plasmids for Sis1, Sse1, or Ssb1 or empty vector controls (n = 3) ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.005 (n = 3).