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Evaluation of bone formation in calvarial defects via micro-CT. Representative micro-CT images of calvarial defects showing mineralized bone formation after treatment with freeze-dried PRP-PCL scaffolds (a,d,g,j), traditional PRP-PCL scaffolds (b,e,h,k) and bare PCL scaffolds (c,f,i,l). The bone tissue in the circle represents the regenerated bone. (m) Regenerated bone formation rate at 2, 4, 8 and 12 weeks after scaffold implantation (* p < 0.05, ** p < 0.01).
