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. Author manuscript; available in PMC: 2017 Aug 10.
Published in final edited form as: Am J Vet Res. 2010 Aug;71(8):909–914. doi: 10.2460/ajvr.71.8.909

Table 2.

Distribution (number [%]) and allele frequencies of Bulldogs (n = 192) and BRTs (101) with normal (both alleles contain guanine [G] at nucleotide No. 542), carrier (1 allele contains G, and the other contains (thymine [T]), and affected (both alleles contain T) genotypes of the SLC2A9 Cys181Phe mutation, associated with hyperuricosuria in these breeds.

Genotype Allele frequency


Breed Normal Carrier Affected G T SE
Bulldog 137 (71.4) 49 (25.5) 6 (3.1) 0.84 0.16 0.02
BRT 27 (26.7) 44 (43.6) 30 (29.7) 0.49 0.51 0.04