Table 3. . Performance of different multilocus variable-number tandem repeat analysis schemes for Mycoplasma pneumoniae strain typing.
| MLVA schemes | VNTR loci included | HGDI† |
|---|---|---|
| MLVA original‡ |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn16 |
0.8967 |
| MLVA-2 |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn003§ |
0.9024 |
| MLVA-3 |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn444 |
0.9183 |
| MLVA-4 |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn108b |
0.9183 |
| MLVA-5 |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn111 |
0.9244 |
| MLVA-6 |
Mpn1, Mpn13, Mpn14, Mpn15 and P1-AGT |
0.9817 |
| MLVA-7 |
Mpn1, Mpn13, Mpn14, Mpn15 and Mpn108a |
0.9841 |
| MLVA-8 |
Mpn13, Mpn14, Mpn15, Mpn003§ and Mpn444 |
0.8366 |
| MLVA-9 |
Mpn1, Mpn108a, Mpn108b, Mpn111 and P1-AGT |
0.9988 |
| MLVA-10 | Mpn1, Mpn108a and P1-AGT | 0.9927 |
Bold indicates relatively unstable loci.
†Based on analysis of 41 isolates as shown in Supplementary Table 10.
‡As described by Degrange et al. [15].
§Same to Mpn103 and Mpn651 in variability and stability but containing a longer repeat unit than the latter two. Longer repeats could be more easily detected than shorter repeats by fragment sizing.
MLVA: Multilocus variable-number tandem repeat analysis; VNTR: Variable-number tandem repeat.