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. 2016 Apr 12;12(16):1947–1955. doi: 10.2217/fon-2016-0061

Table 1. . Studies evaluating androgen deprivation therapy in men with prostate cancer.

Study (year) Study type Summary of findings Ref.
Basaria et al. (2006)
Cross-sectional study
Long-term ADT may increase risk of developing insulin resistance and hyperglycemia in men with prostate cancer
[16]
Braga-Basaria et al. (2006)
Cross-sectional study
Long-term ADT is associated with insulin resistance, lipid alterations and abdominal obesity
[17]
Smith et al. (2002)
Prospective study
Treatment with ADT can lead to increase in weight, fat body mass and decrease in lean body mass in men with nonmetastatic prostate cancer
[19]
Smith et al. (2006) Prospective study Insulin sensitivity decreased with short-term ADT in men with locally advanced or recurrent metastatic prostate cancer [20]

ADT: Androgen-deprivation therapy.