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. Author manuscript; available in PMC: 2017 Dec 7.
Published in final edited form as: Vaccine. 2016 Nov 7;34(50):6243–6249. doi: 10.1016/j.vaccine.2016.10.062

Table 1.

Annualized rates of parapneumonic empyema related hospitalizations per 100,000 children <18 years by vaccination era, United States, 1997–2013

Period All Parapneumonic Empyema Parapneumonic Empyema with Thoracentesis
Estimated Number of Hospitalizations Rate per 100,000 (95% CI) Estimated Number of Hospitalizations Rate per 100,000 (95% CI)
Pre-PCV7 (1997–1999) 4,501 2.1 (1.7, 2.4) 3,827 1.8 (1.5, 2.1)
Early-PCV7 (2001–2005) 11,460 3.1 (2.5, 3.7) 9,742 2.7 (2.1, 3.2)
Late-PCV7 (2006–2009) 10,538 3.6 (2.9, 4.2) 9,015 3.0 (2.4, 3.7)
Post-PCV13 (2011–2013) 4,402 2.0 (1.7, 2.3) 3,748 1.7 (1.4, 2.0)

Footnote: PCV7: 7-valent pneumococcal conjugate vaccine; PCV13: 13-valent pneumococcal conjugate vaccine; CI: Confidence Interval