. 2017 Jun;3(2):105–113. doi: 10.18383/j.tom.2017.00006

Table 3.

Statistical Comparison of Quantitative fMRI Results Between T2prep and EPI BOLD fMRI (n = 8)^†

	T2prep	EPI	P
Activated voxels in respective scans^a
ΔS/S (%)^c	1.58 ± 0.43	1.62 ± 0.46	.872
tSNR^c	61.33 ± 13.20	58.11 ± 14.07	.877
CNR^c	97.51 ± 24.77	94.52 ± 20.55	.823
Inferior frontal lobe including the Broca's area^b
ΔS/S (%)	0.73 ± 0.37	0.23 ± 0.11	.001^*
tSNR	44.66 ± 5.11	38.99 ± 6.12	.576
CNR	33.45 ± 17.15	5.96 ± 4.39	.012^*
Superior temporal lobe including the Wernicke's area^b
ΔS/S (%)	0.47 ± 0.25	0.25 ± 0.14	.049^*
tSNR	68.89 ± 20.17	64.12 ± 18.03	.828
CNR	31.79 ± 8.02	14.20 ± 4.81	.042^*

Abbreviations: T2prep, T2-prepared; tSNR, temporal signal-to-noise ratio; CNR, contrast-to-noise ratio; EPI, echo planar imaging.

^†Each method was performed twice (2 tasks: sentence completion and breath-hold) in all 4 patients, therefore n = 8.

^*P values <.05.

^aSignals averaged over all activated voxels in respective scans.

^bSignals averaged over all voxels (including voxels that did not meet the activation detection criteria described in Methodology) in the inferior frontal and superior temporal lobes, respectively. Regions of interest (ROIs) were manually drawn on the anatomical (FLAIR) image for each patient. The same ROI was used for all scans from each subject.

^cRelative signal change (ΔS/S), tSNR, and CNR are defined in Methodology.