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. 2017 Jul 27;6:159–170. doi: 10.1016/j.omtm.2017.07.006

Figure 8.

Figure 8

Sequences for Validated RORα and Putative Transcription Factor Binding Sites in L7-6 Promoter Are Highly Conserved among Mouse, Marmoset, and Human

Boxed regions are proposed transcription factor binding sites of the L7-6 promoter.37 Numbers above the sequence are relative positions when the transcription initiation codon begins from +1. Notably, the retinoic-acid-receptor-related orphan receptor α (RORα) binding sites completely match between mouse and human, suggesting that the mouse L7-6 promoter effectively works in the human brain as proven in the marmoset brain.