Table 3.

Validity of items about physician-diagnosed COPD and emphysema among men, women and ever-smokers in relation with different spirometry definitions of airway obstruction and COPD

	Airways obstruction (n=212)		COPDGOLD (n=105)		COPDLLN (n=100)
	Value	95% CI	Value	95% CI	Value	95% CI
Physician-diagnosed COPD/emphysema (n=25)
Males (n=14)
Sensitivity	0.063	0.023–0.131	0.100	0.038–0.205	0.105	0.040–0.215
Specificity	0.981	0.964–0.992	0.983	0.967–0.993	0.983	0.967–0.993
PPV	0.429	0.177–0.711	0.429	0.177–0.711	0.455	0.168–0.767
NPV	0.824	0.789–0.856	0.894	0.864–0.920	0.900	0.871–0.925
Females (n=11)
Sensitivity	0.052	0.019–0.109	0.111	0.037–0.241	0.116	0.039–0.251
Specificity	0.988	0.972–0.996	0.988	0.973–0.995	0.988	0.973–0.995
PPV	0.546	0.234–0.833	0.455	0.168–0.766	0.429	0.177–0.711
NPV	0.786	0.748–0.821	0.922	0.900–0.944	0.926	0.900–0.947
Ever-smokers (n=20)
Sensitivity	0.072	0.036–0.125	0.119	0.059–0.208	0.125	0.062–0.218
Specificity	0.980	0.962–0.991	0.981	0.965–0.991	0.981	0.965–0.991
PPV	0.550	0.315–0.770	0.500	0.272–0.728	0.500	0.272–0.728
NPV	0.756	0.719–0.790	0.873	0.843–0.899	0.880	0.851–0.905

Abbreviations: NPV, negative predictive value; PPV, positive predictive value; _LLN, lower limit of normal.