Skip to main content
. 2017 Aug 4;12:2269–2275. doi: 10.2147/COPD.S136308

Table 3.

Validity of items about physician-diagnosed COPD and emphysema among men, women and ever-smokers in relation with different spirometry definitions of airway obstruction and COPD

Airways obstruction (n=212)
COPDGOLD (n=105)
COPDLLN (n=100)
Value 95% CI Value 95% CI Value 95% CI
Physician-diagnosed COPD/emphysema (n=25)
Males (n=14)
 Sensitivity 0.063 0.023–0.131 0.100 0.038–0.205 0.105 0.040–0.215
 Specificity 0.981 0.964–0.992 0.983 0.967–0.993 0.983 0.967–0.993
 PPV 0.429 0.177–0.711 0.429 0.177–0.711 0.455 0.168–0.767
 NPV 0.824 0.789–0.856 0.894 0.864–0.920 0.900 0.871–0.925
Females (n=11)
 Sensitivity 0.052 0.019–0.109 0.111 0.037–0.241 0.116 0.039–0.251
 Specificity 0.988 0.972–0.996 0.988 0.973–0.995 0.988 0.973–0.995
 PPV 0.546 0.234–0.833 0.455 0.168–0.766 0.429 0.177–0.711
 NPV 0.786 0.748–0.821 0.922 0.900–0.944 0.926 0.900–0.947
Ever-smokers (n=20)
 Sensitivity 0.072 0.036–0.125 0.119 0.059–0.208 0.125 0.062–0.218
 Specificity 0.980 0.962–0.991 0.981 0.965–0.991 0.981 0.965–0.991
 PPV 0.550 0.315–0.770 0.500 0.272–0.728 0.500 0.272–0.728
 NPV 0.756 0.719–0.790 0.873 0.843–0.899 0.880 0.851–0.905

Abbreviations: NPV, negative predictive value; PPV, positive predictive value; LLN, lower limit of normal.