Table 2.
Clinical and laboratory characteristics of HIV-infected children during follow-up in Gondar University Hospital, 2015
| Variable | Before ART n (%) | After ART n (%) | P-value |
|---|---|---|---|
| Weight for age | |||
| <5th percentile | 130 (58.6) | 66 (29.7) | |
| ≥5th percentile | 92 (41.4) | 156 (70.3) | 0.000 |
| Height for age | |||
| <5th percentile | 139 (62.6) | 74 (33.3) | |
| ≥5th percentile | 83 (37.4) | 148 (66.7) | 0.000 |
| Weight for height, % | |||
| <70 | 31 (14) | 2 (0.9) | |
| 70–79 | 43 (19.4) | 18 (8.1) | |
| 80–89 | 7 (3.2) | 23 (10.4) | |
| ≥90 | 141 (63.5) | 179 (80.6) | 0.000 |
| Opportunistic infections | |||
| Tuberculosis | 35 (15.7) | 12 (5.4) | |
| Persistent diarrhea | 23 (10.4) | 19 (8.5) | |
| Pneumonia | 50 (22.5) | 54 (24.3) | |
| ¥PCP | 49 (1.8) | 4 (1.8) | |
| *Other opportunistic infections | 36 (16.3) | 19 (8.6) | |
| No opportunistic infections | 74 (33.3) | 114 (51.4) | 0.000 |
| Anemia | |||
| Yes | 95 (42.8) | 42 (18.9) | 0.000 |
| Leukocytes | |||
| Leukopenia | 23 (10.4) | 30 (13.5) | |
| Leukocytosis | 21 (9.5) | 9 (4.1) | |
| Normal | 178 (80.2) | 183 (82.4) | 0.230 |
| Neutrophil count | |||
| Neutropenia | 23 (10.4) | 35 (15.8) | 0.310 |
| Lymphocyte count | |||
| Lymphopenia | 33 (14.9) | 21 (9.5) | 0.051 |
| Thrombocytes | |||
| Thrombocytopenia | 18 (8.1) | 4 (1.8) | |
| Thrombocytosis | 40 (18) | 31 (14) | |
| Normal | 164 (73.9) | 187 (84.2) | 0.550 |
| CD4 cell, % | |||
| <15 | 52 (23.4) | 18 (8.1) | |
| 15–25 | 89 (40.1) | 48 (24.6) | |
| >25 | 81 (36.5) | 156 (70.3) | 0.000 |
Notes:
*
Other = Tuberculosis and pneumonia, otitis media and pyomyositis.
Abbreviations: ART, antiretroviral treatment; PCP, Pneumocystis jirovecii pneumonia.