Table 4. H. pylori population and genotypes.
| Genotype | Total | H. pylori population (%) | ||
|---|---|---|---|---|
| hpAsia2** | hpEurope | hpAsia2-hpEurope | ||
| cagA-negative | 13* | 2 (15.4) | 10 (76.9)*** | 0 |
| cagA-positive | 41** | 25 (61.0) | 11 (26.8) | 1 (2.4) |
| Group 1: vacA s1m1i1d1c1 | 29 | 21 (75.0) | 8 (36.4) *** | 0 |
| Group 2: vacA s1m2i1d1c2 | 6 | 4 (14.2) | 2 (9.1) | 0 |
| Group 3: vacA s1m2i1d1c2 | 1 | 1 (3.6) | 0 (0.0) | 0 |
| Group 4: vacA s1m2i2d2c2 | 5 | 1 (3.6) | 3 (13.6) | 1 (100.0) |
| Group 5: vacA s2m2i2d2c2 | 10 | 1 (3.6) | 9 (40.9) | 0 |
| Total | 51 | 28 | 22 | 1 |
* One strain was excluded because one of the seven housekeeping genes was undetected in the NGS data and because of the poor quality of sequencing results.
**hpAsia2 strains induced greater antral histological severity than hpEurope strains.
*** the hpEurope population contained more cagA-negative and less-virulent vacA genotypes than the hpAsia2 population.