Table 3. Circulating angiogenic T cell (Tang) subsets in healthy controls (HC) and systemic sclerosis (SSc) patients.
CD4+ | CD8+ | CD28+ | CD28null | |
---|---|---|---|---|
HC (n = 18) | 50.2 (43.8−59.5) | 36.7 (26.1−52.8) | 84.2 (77.8−89.0) | 16.3 (12.2−23.4) |
All SSc (n = 39) | 56.0 (42.3−62.0) | 36.3 (29.0−46.8) | 90.4 (80.9−94.0) | 10.2 (6.1−20.3) |
SSc non-DU (n = 21) | 55.8 (42.8−65.1) | 34.2 (28.5−47.3) | 90.3 (81.1−94.0) | 10.1 (5.5−20.2) |
SSc DU (n = 18) | 57.8 (41.9−62.0) | 38.7 (35.2−47.0) | 87.5 (80.4−95.2) | 16.4 (7.2−23.1) |
SSc early/active NVC (n = 20) | 54.4 (42.5−62.4) | 34.9 (28.3−47.5) | 89.9 (81.0−94.0) | 10.2 (5.3−20.2) |
SSc late NVC (n = 19) | 59.6 (42.2−62.0) | 37.4 (34.2−46.8) | 93.0 (80.9−95.0) | 14.0 (6.3−23.0) |
DU, digital ulcers; NVC, nailfold videocapillaroscopy.
Values are the percentage of cells in total CD3+CD31+CXCR4+ Tang cells expressed as median (IQR).