Table 2. Summary of the results of lumbar puncture (LP) in patients with primary progressive multiple sclerosis (PPMS).
CSF parameter | Median (maximum) | interquartile range | Missing data | |||
---|---|---|---|---|---|---|
Total PPMS cohort | LPD | Total PPMS cohort | LPD | Total PPMS cohort (total number = 254) |
LPD (total number = 209) | |
Cell count (/μl) | 2 (101) | 3 (101) | 1–5 | 1–5 | 20 | 10 |
Total protein (mg/l) | 485 (1775) | 485 (1775) | 181–323 | 366–602 | 21 | 10 |
Albumin (mg/l) | 252 (1300) | 247 (1300) | 374–593 | 176–332 | 78 | 63 |
Alb-Q (x103)% | 5.8 (37.8) | 5.8 (37.8) | 4.3-7-8 | 4.2–7.9 | 27 | 17 |
Lactat (mmol/l) | 1.7 (5.6) | 1.7 (2.9) | 1.5–1.9 | 1.5–1.9 | 153 | 127 |
IgG index | 0.7 (6.0) | 0.8 (6.0) | 0.6–1.10 | 0.6–1.1 | 75 | 65 |
IgGloc | 2.70 (271.7) | 3.3 (271.7) | 0–24.4 | 0–24.1 | 75 | 65 |
IgA index | 0.3 (2.3) | 0.3 (2.1) | 0.2–0.3 | 0.3–0.3 | 78 | 68 |
IgAloc | 0 (72.7) | 0 (72.7) | 0 | 0 | 78 | 68 |
IgM index | 0.08 (0.97) | 0.08 (0.97) | 0.05–0.13 | 0.05–0.2 | 78 | 68 |
IgMloc | 0 (4.5) | 0 (2.5) | 0 | 0 | 78 | 68 |
Loc = local synthesis in mg/dl, LPD: diagnostic lumbar puncture.