Table 3. Prevalence of single positive AI against measles (M), Rubella (R) and varicella-zoster virus (Z) and different combinations in our PPMS cohort.
| Positive Antibody index | Measles (M) | Rubella (R) | Varicella Zoster (Z) | M+R+Z- | M+R-Z+ | M-R+Z+ | M+R+Z+ | Positive MRZ-reaction (≥ two AI > 1.4) |
|---|---|---|---|---|---|---|---|---|
| Total PPMS cohort | 24/148 (16.2%) |
7/148 (4.7%) |
15/148 (10.1%) |
13/148 (8.8%) |
13/148 (8.8%) |
11/148 (7.4%) |
40/148 (27.0%) |
77/148 (52.0%) |
| OCB+ | 24/139 (17.3%) |
7/139 (5.0%) |
14/139 (10.1%) |
13/139 (9.4%) |
12/139 (8.6%) |
11/139 (7.9%) |
35/139 (25.2%) |
71/139 (51.1%) |
| OCB- | 0/9 |
0/9 |
1/9 (11.1%) |
0/9 |
1/9 (11.1%) |
0/9 |
5/9 (55.6%) |
6/9 (66.7%) |
| LPD | 18/127 (14.2%) |
7/127 (5.5%) |
13/127 (10.2%) |
11/127 (8.7%) |
12/127 (9.4%) |
11/127 (8.7%) |
34/127 (26.8%) |
68/127 (53.5%) |
OCB+: patients with positive oligoclonal bands, OCB-: patients with negative oligoclonal bands, LPD: diagnostic lumbar puncture.