. Author manuscript; available in PMC: 2018 Mar 15.

Published in final edited form as: Spine (Phila Pa 1976). 2017 Mar 15;42(6):385–393. doi: 10.1097/BRS.0000000000001767

TABLE 4.

Sensitivity and Specificity

Study	Year	Number of Patients	Total Incidence of Neurologic Injury (%)	Neurologic Injury Risk With ION (%)	Neurologic Injury Risk Without ION (%)	Sensitivity	Specificity	False Negative	False Positive
Bose et al¹⁴	2004	119	3 (2.5)	NR	NR	0.33	0.96	0.67	0.04
Bouchard et al¹⁵	1996	32	0 (0)	NR	NR	N/A	1.00	N/A	0.00
Gokaslan et al¹⁶	1997	16	0 (0)	NR	NR	N/A	1.00	N/A	0.00
Lee et al¹⁷	2006	Total: 1445 Corpectomy: 483	Total: 2 (0.01) Corpectomy: 2 (0.4)	NR	NR	1.00	0.82	0.00	0.18
Sebastian et al¹⁸	1997	Total: 210 Corpectomy: 80	Total: 0 (0) Corpectomy: 0 (0)	NR	NR	N/A	0.81	N/A	0.19
Smith et al¹⁹	2007	1039	1 (0.09)	1/577 (0.17)	0/462 (0)	0.00	0.99	1.00	0.01
Taunt et al²⁰	2005	163	1 (0.6)	NR	NR	0.67	0.98	0.33	0.02
Xu et al²¹	2011	57	2 (3.5)	NR	NR	0.67	0.96	0.00	0.04
Cole et al²²	2014	22768	28 (0.12)	5/5700 (0.09)	23/17068	N/A	N/A	N/A	N/A
Khan et al²³	2006	508	12 (2.4)	NR	NR	0.77	1.00	0.23	0.00

Data for each study’s individual sensitivity and specificity analysis.

The values represent the total sensitivity and specificity for all patients included in the study, the total value in “Number of Patients.”

ION indicates intraoperative neuromonitoring; NR, not reported.