Table 4. Results of Haplotype Associations with Intracranial Aneurysm.
SNPset | Haplotype | MHF* | Chi-square† | pasym† |
---|---|---|---|---|
rs3792801-rs2303656 | TA | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs2303656-rs10519694 | AC | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs3853401-rs3900446 | TT | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs3900446-rs763497 | CG | 0.113/0.000 | 18.96 | 1.3×10−5 |
rs10040971-rs17148773-rs3792801 | TCT | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs17148773-rs3792801-rs2303656 | CTA | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs3792801-rs2303656-rs10519694 | TAC | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs2303656-rs10519694-rs2956540 | ACG | 0.000/0.070 | 11.52 | 6.9×10−4 |
rs10040971-rs17148773-rs3792801-rs2303656 | TCTA | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs17148773-rs3792801-rs2303656-rs10519694 | CTAC | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs3792801-rs2303656-rs10519694-rs2956540 | TACG | 0.000/0.070 | 11.52 | 6.9×10−4 |
rs2303656-rs10519694-rs2956540-rs1800449 | ACGA | 0.000/0.070 | 11.54 | 6.8×10−4 |
rs10040971-rs17148773-rs3792801-rs2303656-rs10519694 | TCTAC | 0.000/0.069 | 11.39 | 7.4×10−4 |
rs17148773-rs3792801-rs2303656-rs10519694-rs2956540 | CTACG | 0.000/0.070 | 11.52 | 6.9×10−4 |
rs3792801-rs2303656-rs10519694-rs2956540-rs1800449 | TACGA | 0.000/0.070 | 11.54 | 6.8×10−4 |
rs10040971-rs17148773-rs3792801-rs2303656-rs10519694-rs2956540 | TCTACG | 0.000/0.070 | 11.52 | 6.9×10−4 |
rs17148773-rs3792801-rs2303656-rs10519694-rs2956540-rs1800449 | CTACGA | 0.000/0.070 | 11.54 | 6.8×10−4 |
rs10040971-rs17148773-rs3792801-rs2303656-rs10519694-rs2956540-rs1800449 | TCTACGA | 0.000/0.070 | 11.54 | 6.8×10−4 |
MHF, minor haplotype frequency; SNP, single nucleotide polymorphism.
*MHF of case (left) and control (right), †Asymptotic chi-square statistics and p value were estimated by the omnibus-based haplotype association test.