Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 9;7:360. doi: 10.3389/fcimb.2017.00360

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Contreras, Alberdi, Fernández De Mera, Krull, Nijhof, Villar and De La Fuente.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Criteria for the selection of candidate tick protective antigens. (A) Annotation and criteria used for the selection of candidate tick protective antigens. The log2 normalized fold change between infected and uninfected tick samples (P < 0.00003) is shown. Bold numbers indicate highly differentially regulated genes (log2 normalized fold change > 5.64) and highly differentially represented proteins (log2 normalized fold change > 3.90) between infected and uninfected tick samples. The selection criteria were (i) highly differentially up-regulated genes in at least two samples, (ii) highly down-regulated genes in at least one sample, (iii) highly differentially over-represented proteins and identified in the I. scapularis proteome, (iv) highly differentially under-represented proteins and identified in the I. scapularis proteome, and/or (v) putative BP in tick-pathogen and tick-host interactions. (B) The GO for BP of selected candidate protective antigens was done with Blast2GO software (version 3.0; http://www.blast2go.com).