Table 3.

Neuropsychological test findings summary table (for tests used more than once) in studies of bipolar disorder (BD) and temporal lobe epilepsy (TLE).

Measure	BD		TLE		Pre- to post- surgical		Laterality effects
	Use in studies, number of participants BD	BD < HC sig	Use in studies, number of participants TLE	sig	↑	↓
Executive function
WCST	12 studies	11	2 studies	1	↑1
	BD n = 859, healthy controls (HC) n = 676		Right temporal lobe (RTL) n = 44, left temporal lobe (LTL) n = 49, HC n = 22
COWAT(FAS)	5 studies	2	2 studies	2	↑1		Higher score LTL group pre- assoc. with greater impairment post-surg
			RTL n = 33, LTL n = 38
	BD n = 133, HC n = 130
TMT-B	9 studies	7
	BD n = 513, HC = 339
Stroop	10 studies	7
	BD n = 895, HC = 642
Hayling Sentence Completion Test	2 studies	2
	BD n = 25, HC n = 73
CANTAB: Intra Extra Dimensional Set Shifting	2 studies	2
	BD n = 140, HC n = 78
CANTAB: Stockings Problem	2 studies	2
	BD n = 140, HC n = 78
Verbal memory
CVLT	5 studies	3	7 studies	6		↓6	Post-surg LTL decline 6
	BD n = 233, HC n = 153		RTL n = 158, LTL n = 215, HC n = 10				RTL > LTL 1
RAVLT	3 studies	2	5 studies	5		↓5	Post-surg LTL decline 5
	BD n = 141, HC = 79		RTL n = 78, LTL n = 176, HC n = 28
Verbal comprehension: WAIS Vocab	4 studies	0
	BD n = 187, HC n = 173
WMS-R: Logical Memory			6 studies	4	↑3	↓1	LTL < RTL 1
			RTL n = 206, LTL n = 256, HC n = 28
WMS-R: Verbal Paired Associates			4 studies	4	↑2	↓1	LTL < RTL 1
			RTL n = 119, LTL n = 151, HC n = 28
Token Test			2 studies	1	↑1		Post-surg LTL improved 1
			RTL n = 34, LTL n = 47
VLMT: Verbaler Lern- und Merkfähigkeitstest			2 studies	2		↓2
			RTL n = 83, LTL n = 82
Visuospatial memory
ROCFT	2 studies	0	3 studies	2	↑1		LTL < RTL 1
	BD n = 65, HC n = 47		RTL n = 25, LTL n = 62, HC n = 36
WMS: Visual reproduction	3 studies	0	2 studies	0
	BD n = 105, HC n = 78		RTL n = 27, LTL n = 29
CANTAB: Spatial recognition memory	2 studies	2
	BD n = 140, HC n = 78
CANTAB: Pattern Recognition Memory	2 studies	2
	BD n = 140, HC n = 78
CANTAB: Paired Associates Learning	2 studies	2
	BD n = 140, HC n = 78
WMS-R: Design Memory			4 studies	2	↑1	↓1	RTL decline 1
			RTL n = 78, LTL n = 93, HC n = 28
WMS-R Visual Reproduction			5 studies	2	↑1	↓1	RTL decline 1
			RTL n = 241, LTL n = 484, HC n = 28
WMS-III: Face Test			1 study	1		↓1	RTL decline 1
			RTL n = 16, LTL n = 10
Graduate Hospital Facial Memory			3 studies	3	↑1		RTL < LTL 2
			RTL n = 71, LTL n = 46, HC n = 10
Benton Visual Retention			2 studies	0
			RTL n = 31, LTL n = 72
Diagnosticum für Cerebralschädigung			3 studies	2		↓1
			RTL n = 83, LTL n = 253
Spatial ability
WAIS: Block design	4 studies	0
	BD n = 124, HC n = 109
Attention span
WAIS: Digit Span	3 studies	2	4 studies	0
	BD n = 103, HC n = 89		RTL n = 93, LTL n = 150, HC n = 15
TMT-A (also processing speed)	10 studies	8
	BD n = 513, HC = 339
WAIS: Digit Symbol (also processing speed)	3 studies	3
	BD n = 91, HC = 86
CANTAB: Rapid Visual Information	2 studies	2
	BD n = 140, HC n = 78
Adult Memory and Information Processing Battery (AMIPB)			2 studies	2	↑1	↓1
			RTL n = 279, LTL n = 334
Sustained attention
CPT	4 studies	2
	BD n = 84, HC n = 84
Working memory
SWMT	2 studies	0
	BD n = 30, HC n = 30
N-Back	2 studies	0
	BD n = 45, HC n = 47
WAIS: Letter Number Sequencing	3 studies	3
	BD n = 126, HC n = 126
WMS-III: Letter Number Sequencing	2 studies	3
	BD n = 140, HC n = 78
CANTAB: Spatial Working Memory	2 studies	2
	BD n = 140, HC n = 78

↑ refers to an increase, ↓ a decrease from pre- to post-surgery, sig refers to the number of studies with a significant result, laterality comments only significant main effects or interactions are discussed.