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. 2017 Aug 10;7:7814. doi: 10.1038/s41598-017-08412-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) BMP-2 release in PBS of different groups for 21 days, (B). VEGF-165 release in PBS of different groups for 21 days. In the figure K represents control group- pure hydrogel, B for BMP-2 loaded-hydrogel, V for VEGF-165 loaded-hydrogel and BV for hydrogel loaded with both BMP-2 and VEGF-165.