Table 3.
Viral ORFs with Malacoherpesviridae-specific protein domains.
| ORF annotation | Virus ID | Domain ID | No. of MAL gene | Domain occurrence | |
|---|---|---|---|---|---|
| Other viruses | Mollusk genomes | ||||
| Apoptosis inhibitor | 1, 2, 3, 4, 5, 6 | BIR | 18 (6) | dsDNA and RNA viruses | Yes |
| Ribonucleotide reductase, s.s. | 1, 2, 3, 4 | Ribonuc_red_sm, Fic | 4 (1) | Caudovirales, Nimaviridae, Nudiviridae | Yes |
| Guanylate kinase | 5, 6 | Guanylate_kin | 2 (1) | Poxviridae, Caudovirales | Yes |
| DNA ligase | 5, 6 | DNA_ligase_A_M, DNA_ligase_A_N, DNA_ligase_A_C | 2 (1) | dsDNA viruses | Yes |
| Eukaryotic translation initiation factor-5 | 5 | eIF-5_eIF-2B | 1 (1) | Baculoviridae, Marseilleviridae | Yes |
| Exonuclease | 1, 2, 3, 4 | EXO5 | 4 (1) | / | Low similarity |
| Exonuclease | 5, 6 | PDDEXK_1 | 2 (1) | dsDNA viruses, Caudovirales | Low similarity |
| / | 5, 6 | SprT-like | 2 (1) | Caudovirales, Baculoviridae | Low similarity |
| RNA helicase | 5, 6 | ResIII | 2 (1) | dsDNS and ssRNA viruses | Low similarity |
| Zinc finger | 1, 2, 3, 4 | zf-RING_5 | 4 (1) | Mimiviridae | Low similarity |
| RNA ligase | 5, 6* | RNA_lig_T4_1 | 2 (1) | Caudovirales, Baculoviridae | No |
| Methyltransferase/ | 5 | OrfB_Zn_ribbon, | 1 (1) | Caudovirales Mimiviridae Phycodnaviridae | No |
| transposase | OrfB_IS605, | ||||
| HTH_OrfB_IS605 | |||||
From left to right: putative ORF annotation and Malacoherpesviridae family members in which they are present (see numbering in Table 1), domain description, total number of Malacoherpesviridae genes showing the specified domain (in parentheses, the number of unique genes), and occurrence of the same domain in other viral families as well as in mollusk genomes.
*
Partial or incomplete sequences are also present in bivalve Malacoherpesviridae.