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. 2017 Jun 15;60(9):1813–1821. doi: 10.1007/s00125-017-4322-3

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — sFLT-1 inhibited VEGF-induced tube formation in vitro. (a–d) HUVECs were cultured in the presence or absence of VEGF-A (10 ng/ml) and/or sFLT-1, and the number of branch points was measured. (e) Summary of the total number of branch points measured in five fields under each condition. Boxes represent 1st and 3rd quartiles; whiskers represent minimum and maximum number of branch points; horizontal line represents median number of branch points. ***p < 0.001, one-way ANOVA. Scale bars, 100 μm