Table 1.
Demographic, clinical and neuropsychological data of the three groups
| Variables | Diabetic cirrhosis (n = 17) | Non-diabetic cirrhosis (n = 17) | Healthy controls (n = 17) | P value |
|---|---|---|---|---|
| Age (y) | 54.8 ± 8.3 | 53.4 ± 5.9 | 54.4 ± 7.9 | 0.842a |
| Gender (M/F) | 12/5 | 12/5 | 12/5 | 0.999b |
| NCT-A (s) | 52.8 ± 20.0 | 48.1 ± 12.8 | 36.8 ± 9.1 | 0.018c |
| DST (n) | 34.5 ± 10.9 | 40.5 ± 12.5 | 52.4 ± 8.9 | 0.001a |
| Child-Pugh scale (A/B/C) | 15/1/1 | 15/1/1 | none | 0.999c |
| HE (N/M/S) | 15/1/1 | 15/1/1 | none | 0.999c |
| Ascites (N/M/S) | 9/5/3 | 11/6/0 | none | 0.193c |
| TB (μ mol/L) | 26.9 (36.2−15.8) | 28.2 (38−17.1) | none | 0.692c |
| Albumin (g/L) | 35.8 ± 6.5 | 35.1 ± 6.0 | none | 0.804d |
| PT (s) | 14.1 (15.5−13.1) | 16.2 ± 3.0 | none | 0.063c |
| Ammonia (μ mol/L) | 54.5 ± 24.7 | 39 (76.5−11.5) | none | 0.480c |
| ALT (U/L) | 39.6 ± 27.9 | 31 (39−22) | none | 0.823c |
| AST (U/L) | 41.6 ± 21.3 | 39 (55−27.5) | none | 0.796c |
| Glucose (mmol/L) | 7.3 ± 1.3 | 4.6 (5.1−4.2) | none | 0.001c |
| Cirrhosis duration (y) | 3.2 ± 2.9 | 2.4 ± 2.5 | none | 0.380d |
Mean ± standard deviation; Median and inter-quartile range [M (QU-QL)].
P values indicate significant differences across groups.
aanalysis of variance; bchi square test; ck-independent samples nonparametric tests dtwo-sample t tests.
y = year; M = male; F = female; NCT-A = number connection test type A; DST = digit symbol test; s = second; n = number; HE = hepatic encephalopathy; N = none; M = mild; S = severe; TB = total bilirubin; PT = prothrombin time; ALT = alanine transaminase; AST = aspartate transaminase.