Biological N‐cycle illustrating major metabolic processes (number coded) with associated known key enzymes. Number‐coded metabolic processes: 1, nitrate reduction; 2, denitrification; 3, nitrogen fixation; 4, aerobic ammonia oxidation; 5, aerobic nitrite oxidation; 4+5, comammox; 6, dissimilatory nitrite reduction to ammonium (DNRA); 7, anaerobic ammonia oxidation. Nar/Nap, dissimilatory nitrate reductase; NirK/NirS, dissimilatory NO‐forming nitrite reductase; Nor, nitric oxide reductase; Nod; nitric oxide dismutase; Nos, nitrous oxide reductase; Nif, nitrogenase; Amo, ammonia monooxygenase; Hao, hydroxylamine oxidoreductase; Nxr, nitrite:nitrate oxidoreductase; Nrf, dissimilatory ammonia‐forming nitrite reductase; Hzs, hydrazine synthase