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. 2017 Jun 22;117(15):10502–10566. doi: 10.1021/acs.chemrev.7b00151

Scheme 6. Application of Chiral γ-Hydroxy Butenolide 9 for the Total Synthesis of (−)-Azaspiracid-1.

Scheme 6

TMS = trimethylsilyl, PMB = p-methoxybenzyl.