FIG 6.

Differences in the numbers of Gag mutations between Gag sequences derived from mothers and those derived from infants. CD8⁺ T cell escape mutations in defined Gag epitopes (30) in mother-infant pairs were enumerated. In 17 MIPs, the numbers of mutations were identical in the mother and infant sequences, but in the remaining 11 pairs, the infants had one or two fewer mutations than the sequences from the mothers (P = 0.001 as determined by a Wilcoxon matched-pairs signed-rank test).