FIG 7.

Study population. Plasma samples were obtained for 44 transmitter mothers and 40 infants. Gag-protease was successfully sequenced for 29 MIPs, and Gag-protease-driven replication capacities were successfully determined for 31 MIPs. However, altogether, replication capacity assays and sequencing were successful for 28 MIPs. Altogether, Gag-protease-driven replication capacities were determined for 41 MIPs (31 from the Durban laboratory and 10 from an independent laboratory). The mode of transmission within 28 out of the 41 MIPs was in utero mother-to-child transmission (MTCT). The mode of transmission for the remaining 13 MIPs was intrapartum transmission.