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. 2017 Sep;92(3):338–346. doi: 10.1124/mol.117.108472

Fig. 6.

Fig. 6.

T153C increases block by another low-affinity blocker, VU714. (A) Chemical structures of VU714 and ML418; (B) Mean ± S.D. percent inhibition by 0.3 μM ML418 or 3 μM VU714 of M125R-T153C mutant. Data were analyzed using unpaired t test. *P < 0.05 statistically significantly different from the respective control background (Kir7.1-M125R), n ≥ 5. N.S., non-significant.