. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Arthritis Rheumatol. 2017 Mar;69(3):529–541. doi: 10.1002/art.39862

Table 3. Coronary artery calcification relation with disease activity score and genetic risk score.

	DAS28 (beta coef. 95% CI, p)

	Unadjusted	Model #1	Model #2	Model #3
	Univariate model	Adjusted for age and sex	Adjusted for Model 1 plus diabetes, hypertension, smoking and dyslipidemia	Adjusted for Model 1 and 2 plus GRS

CAC > 0	0.15 (-0.13-0.43), 0.30	0.37 (0.04-0.70), 0.03	0.09 (-0.27-0.45), 0.62	0.08 (-0.28-0.44), 0.65
CAC > 10	0.24 (-0.04-0.52), 0.09	0.48 (0.16-0.80), 0.00	0.34 (-0.01-0.68), 0.06	0.32 (-0.02-0.68), 0.07
CAC > 75th	0.39 (0.10-0.68), 0.01	0.46 (0.16-0.76), 0.00	0.28 (-0.05-0.60), 0.09	0.27 (-0.06-0.59), 0.10
CAC > 90th	0.52 (0.18-0.86), 0.00	0.55 (0.21-0.89), 0.00	0.43 (0.04-0.81), 0.03	0.42 (0.04-0.81), 0.03

	Genetic risk score (beta coef. 95% CI, p)
	Unadjusted	Model #1	Model #2

	Univariate model	Adjusted for age and sex	Adjusted for Model 1 plus diabetes, hypertension, smoking and dyslipidemia

CAC > 0	- 0.03 (-0.06--0.00), 0.03	-0.01 (-0.04-0.02), 0.51	-0.01 (-0.05-0.03), 0.66
CAC > 10	- 0.04 (-0.06--0.01), 0.04	-0.01 (-0.04-0.03), 0.68	-0.01 (-0.04-0.04), 0.95
CAC > 75th	- 0.01 (-0.04-0.02), 0.59	0.00 (-0.03-0.03), 0.91	0.01 (-0.03-0.05), 0.72
CAC > 90th	0.01 (-0.03-0.04), 0.69	0.01 (-0.03-0.05), 0.57	0.02 (-0.03-0.06), 0.50

CAC = coronary artery calcification; CI = confidence interval