. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: Exp Eye Res. 2017 Apr 14;160:106–115. doi: 10.1016/j.exer.2017.04.003

Table 3. Mitochondria Count, Diameter, Area and Density in control explants.

CONTROL	#1- ONH	#2	#3	#4	#5- Distal ON
Mitochondria Count	322	412	408	347	280
Mean Diameter ± StDev (μm)	1.5 ± 1.1	1.3 ± 1.1^**	1.3 ± 1.0^**	1.1 ± 0.8^*	1.2 ± 0.9^*
Total Area (μm²)	757	774	689	430	411
Density (mitochondria/mm²)	16,110 ± 3,159	20,600 ± 4,039^*	20,400 ± 4,000^*	17,342 ± 3,400	14,010 ± 2,747
N	10	9	9	6	5
% Decrease from Total area #1		-2.3%^**	9%^**	43%^**	46%^**

Total Area= Area of all mitochondria with image window

Density= number of mitochondria in window (200μm × 100 μm)

For Diameter and Decrease from Total area, p-values compare location # 1 proximal to the eye (ONH) to distal locations along the nerve:

= p ≤ 0.05, and

^**

= p ≤0.01.

Mean ± standard deviation